New Psychiatric Paradigm
The human cognitive-emotional system is universal with its structure having been modeled by evolution. Views of oneself in relation to others is primary determinate of emotional/psychological state. The nature and strength of these views is determined by social interaction (particularly in childhood) setting innate parameters which are universal, can be formally modeled, and have mostly to do with dominance and subordination.
A formal model of these parameters and a thorough history of the patient's significant (to them) social interactions would enable a diagnosis based upon an understanding about how the mind as an organ responds to exposure to different social experiences rather than placement into a category defined by statistical associations of symptoms (as is done now using the DSMIV). There are deep parallels to be drawn between the brain's exposure to social stimuli and ideas (memes) and a physical organ's exposure to physical entities.
Under this system pathologies can be divided into two major classes: those due to a defect in the universal parameters, and those due to the parameters being set in a way which decreases quality of life for the patient and is no longer adaptive (although it once was in the environment we evolved in).
This perspective readily provides satisfying explanations for some otherwise puzzling psychological phenomena (e.g. Stockholm syndrome, depression/anxiety, sexual abuse/sex worker association, inappropriate childhood assumption of responsibility, etc.)